DOS 2018

DOS Kongressen 2018 · 65 Five-year outcome of combined autologous bone and articular cartilage chips transplantation for osteochondral lesions Bjørn Borsøe Christensen, Casper Bindzus Foldager, Morten Lykke Olesen, Jonas Jensen, Martin Lind Orthopedics, Horsens Regional Hospital; Orthopedics, Hospital of Southern Jutland; Radiology, Aarhus University Hospital; Orthopedics, Aarhus University Hospital Background: Osteochondral defects are frequent and difficult to treat. There are numerous available treatment methods, but no gold standard treatment has been established. We present 5-year data on a one-step, autologous bone and articular cartilage chips transplantation, Autologous Dual-Tissue Transplantation (ADTT). ADTT is an easily applicable, low-cost treatment option for osteochon- dral repair. Purpose / Aim of Study: To investigate the long-term subjective and func- tional clinical outcome of ADTT. Materials and Methods: Eight patients (age 32 ± 7.5 years) suffering from osteochondritis dissecans (OCD) in the knee were enrolled. The OCD lesion was debrided filled with bone and particulated cartilage biopsies, and fixed with fibrin glue. Evaluation was performed using patient reported outcome scores preop- eratively and at 1, 2 and 5 years postoperative. MRI and CT was used for evalu- ation pre-operatively and at one year. Findings / Results: The IKDC score increased from 35.9 to 68.1, 75.4 and 78.2 after 1, 2 and 5 years, respectively (p<0.01). The Tegner score improved from 2.5 to 4.7, 5.1 and 5.1 at 1, 2 and 5 years (p<0.05). KOOS subscores Sport/ rec, and quality of life improved at one year and the improvements persisted at two and five years (p<0.05). KOOS pain improved after 5 years (p<0.01). Cartilage tissue repair evaluated using MOCART score improved from 22.5 to 52.5 at one year (p<0.01). CT imaging demonstrated very good subchondral bone healing with all 8 patients having a bone filling of >80% at one year. Conclusions: Treatment of OCD with ADTT resulted in very good subchondral bone restoration and good cartilage repair. Significant improvements in patient reported outcome was found at 1 year postoperative and the improvements persisted at two and five years. This study suggests ADTT as a promising, low- cost, treatment for osteochondral injuries. 8.

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