DOS 2018

DOS Kongressen 2018 · 201 Ioban prevents intra-operative contamination Anne Brun Hesselvig, Anders Odgaard, Magnus Arpi, Thomas Bjarnsholt, Frank Madsen Ortopædkirurgisk Afdeling, Gentofte Hospital; Klinisk Mikrobiologisk Afdeling, Herlev Hospital; Costerton Biofilm Center, Panum Instituttet; Ortopædkirurgisk Afdeling, Aarhus Universitetshospital Background: Infection following joint replacement surgery is a catastrophic complication. Many prophylactic procedures have been implemented to prevent peri-prosthetic infection but dispite this the infection rate is steady at 1-2%. The hypotheses for the present research project are 1) that the patient’s skin is the main source for intraoperative microbial contamination and 2) that intraop- erative contamination can be reduced by using an iodine impregnated incisional drape. Purpose / Aim of Study: The purpose of the project is to gain insight into the etiology of postoperative infection following joint replacement surgery with in- traoperative contamination as our focal point. Specifically, we want to examine whether iodine impregnated incisional drape prevents intraoperative contami- nation and consequently averts infection. Materials and Methods: To examine whether Ioban diminishes the risk of intraoperative contamination, a transregional, prospective, two arm study of 1200 patients undergoing knee arthroplasty surgery was performed. All pa- tients were swabbed during surgery and the surgeons’ glove was also examined for bacteria. Findings / Results: 1135 operated patients for either TKA or UKA were el- igible for analysis, 299 patients from Region Midt and 837 in Region H, re- spectively. The overall contamination rate was 12,5 %. 56/570 (9,82%) were contaminated in the Ioban group and 86/565 (15,22%) in the control group (chi-square test) (P=0,006). Conclusions: Ioban is a useable preventative measure for intra operative con- tamination. 142.