DOS 2018

DOS Kongressen 2018 · 197 Percutaneous vertebroplasty is safe and effective for cancer-related vertebral compression fractures Andreas Ole Kirkeggard, Simon Thorbjørn Sørensen, Dorthe Schøler Ziegler, Leah Carreon, Mikkel Østerheden Andersen, Rikke Rousing Center for Spine Surgery & Research, Middelfart Hospital Background: In 2012 there were 14.1 million new cancer cases worldwide. The frequency of metastasis to the spine depends on the primary cancer, with the majority being breast, lung, and prostate. Traditional pain- relieving therapies include analgesics, bed rest, steroids, radiotherapy etc. are often not an effec- tive treatment in cancer patients with painful vertebral fractures due to spinal metastasis. Traditional spinal surgery in general anesthesia is usually not an op- tion in patients with advanced cancer and poor general condition. Percutaneous vertebroplasty (PVP) has been reported as a minimal invasive treatment option with apparent rapid pain relief compared to the other conventional treatment options. Purpose / Aim of Study: The objective of this study was to assess the safety and efficacy of PVP on patients with malignant spinal lesions at a single site. Materials and Methods: From the National Danish Surgical Spine database, DaneSpine, 30 consecutive cancer patients with vertebral fractures who un- derwent PVP from 2013 to 2017 were identified. From DaneSpine EuroQOL- 5D (EQ-5D) and Oswestry Disability Index (ODI) scores were collected pre- and postoperatively. Incidence of complications and PMMA leaks was extracted from review of medical records and plain postoperative x-rays. Findings / Results: The mean improvement in EQ-5D scores from baseline was 0.30 (p<0.01) after 3 months, and 0.25 (p=0.01) after 1 year. ODI im- proved from 44.1 to 23.3 (p<0.01). Despite a cement leakage rate of 14.8 %, no patients presented any clinically significant symptoms. Conclusions: PVP is a safe procedure providing a statistically significant and clinically relevant improvement in quality of life and function. Our findings may provide useful information to health care professionals treating cancer patients with painful malignant spinal lesions. Conflict of interest: Leah Carreon: member of editorial Advisory Board 138.