DOS 2020

DOS Kongressen 2020 · 177 Venous thromboembolism after fast-track unicompartmental knee arthroplasty – a prospective multicentre cohort study of 3,927 procedures. Pelle Baggesgaard Petersen, Christoffer Calov Jørgensen, Kirill Gromov, Henrik Kehlet, on behalf of the Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group Section for Surgical Pathophysiology, Rigshospitalet; Department ofOrthopaedic Surgery, Hvidovre Hospital Background: Unicompartmental knee arthroplasty (UKA) has increased due to potential favourable complication rates when compared to total knee arthro- plasty (TKA). Although venous thromboembolism (VTE) is a well-documented complication after TKA limited data is available after UKA and mostly presented as secondary findings in observational comparisons to TKA. There is a lack of fast-track UKA VTE studies and no guidelines on thromboprophylaxis. Purpose / Aim of Study: We aimed at describing in details the 90-day inci- dence and time course of VTE after UKA within a multicentre fast-track col- laboration. Materials and Methods: We used an observational cohort study design from 8 dedicated fast-track centres with prospective collection of preoperative risk- factors, complete follow-up on length of stay (LOS), 90-day readmissions and mortality from the Danish National Patient Registry and analysis of health re- cords if LOS > 2 days or an ICD-10 code of VTE. Due to limited events we refrained from analysis of independent risk-factors. Findings / Results: In 3,927 procedures (46.1% males, mean age 66.2 (SD 9.4) years) median LOS was 1 [IQR 0-1] day and 7.5% had LOS > 2 days. The 90-day incidence of VTE was 16 (0.41%) and 14 (0.37%) when excluding pre- operatively anticoagulated patients. There were 5 (0.13%) pulmonary embo- lisms and 11 (0.28%) deep-vein thrombosis after median 18 [11.75-35.25] days. 90-day mortality was 3 (0.08%) with no fatal PE or initial postoperative VTE. Conclusions: The 90-day incidence of VTE after fast-track UKA was 0.41% (0.37% when excluding preoperatively anticoagulated patients), which is com- parable to reports of 0.39% VTEs after fast-track TKA in the same departments. Investigations on risk-factors are needed for optimizing thromboprophylaxis. 156.