DOS 2019

DOS Kongressen 2019 · 165 The association between socioeconomic position and tumour size, grade, stage, and mortality in Danish sarcoma patients – a national, observational study from 2000 to 2013. Mathias Rædkjær, Katja Maretty-Kongstad, Thomas Baad-Hansen, Akmal Safwat , Michael Mørk Petersen, Johnny Keller, Peter Vedsted Department of Orthopedic Surgery, Aarhus University Hospital; Department of Pathology, Aarhus University Hospital; Department of Orthopedic Surgery, Aarhus University Hospital; Department of Oncology, Aarhus University Hospital; Department of Orthopedic Surgery, Rigshospitalet, University Hospital of Copenhagen; Department of Orthopedic Surgery, Aarhus University Hospital; The Research Unit of General Practice, Aarhus University Background: Sarcoma is a rare, heterogenic type of cancer that originates from muscle, bones and connective tissue. Less than 1% of newly diagnosed cancer pa- tients have sarcoma. Survival in sarcoma patients depends on a range of tumour re- lated prognostic factors. An association between cancer survival and socioeconomic position is known for other cancers. Purpose / Aim of Study: The aim of this study was to examine the relations be- tween three socioeconomic factors and the risk of presenting with known prog- nostic factors (size, grade, stage) and the overall mortality of the different socio- economic and prognostic factors in 1919 patients treated for sarcoma in Denmark 2000-2013. Materials and Methods: Patients with sarcoma in extremities or trunk wall aged 30 years or more at diagnosis were identified in the Danish Sarcoma Registry, and linked on an individual level to Danish national registries. We obtained data on edu- cational level, disposable income and cohabitation status. Odds ratios (ORs) were estimated for the association between the socioeconomic factors and grade, stage and tumour size. Survival analyses were performed using Cox proportional hazard models and Kaplan Meier survival curves. Findings / Results: In adjusted analyses, educational level, income and cohabitation status were not associated with grade, stage or tumour size at the time of diagnosis. Patients with a short education, low income, who lived alone, with comorbidity or a large tumour had a significantly higher mortality. Conclusions: In this nationwide, multicentre, population-based study we found that soft tissue sarcoma patients living alone had significantly greater risk of pre- senting with a large tumour at time of diagnosis. Patients with a short education, low income, who lived alone, had a statistically significant higher mortality. Thus, the social differences in mortality seems to be related to treatment aspects rather that the diagnostic process. More attention on socioeconomic factors in the treatment of sarcomas is needed in order to improve survival in patients with lower socioeco- nomic position. 121.