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· DOS Abstracts
Regional differences between US and Europe in
radiological osteoarthritis and self assessed quality of
life in patients undergoing Total Hip Replacement (THR)
surgery
Kirill Gromov, Meridith Greene, Nanna Sillesen, Peter Gebuhr, Anders Troelsen,
Henrik Malchau
Department of Orthopaedic Surgery, Copenhagen University Hospital
Hvidovre; Harris Orthopaedic Laboratory, Massachusetts General Hospital
Background:
Precise indications for THR remain unclear and regional differ-
ences might exist in selecting patients for surgery.
Purpose / Aim of Study:
In this study we investigate radiological grade of OA
and self-reported quality of life in patients undergoing THR in US and Europe
Materials and Methods:
There are 909 patients from 16 centers in the USA
and Europe enrolled into a prospective 10year outcome study. All patients were
operated using an uncemented RingLoc® or Regenerex® cup and a Biomet® stem
of surgeons’ choice. Recorded patient demographics included age, gender, BMI
and Charnley score. Preoperative grade of OA was recorded using Tönnis clas-
sification as well as JSW. Self reported survey data included pain visual analogue
scale (VAS), EQ-5D, SF36, Harris Hip, and UCLA scores that were recorded pre-
operatively and at 1 year follow up.
Findings / Results:
Patients in US were significantly younger (61.4vs 64.2;
p<0.001) and had a higher BMI (29.9vs 27.4; p<0.001). More patients with
mild Tonnis OA grade underwent surgery in US compared to Europe (5.3% vs
2.2%, p=0.046). Patients in the US had significantly higher pain VAS (6 vs 5;
p=0.004) and significantly lower SF-36 Physical Function (29.7 vs 33.9;
p=0.003), while having significantly higher EQ VAS scores (78 vs 66; p<0.001)
preoperatively.
Conclusions:
Patient demographics and disease severity according to radiolog-
ical OA grade and self- reported survey scores vary between United States and
Europe. This knowledge can be used in the interpretation of US and European
based studies on outcome following THR.
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